Epigenetic’s Science is composed by award winning author, Raoul Pedretta. Great bye, genetically encoded genes… the first book in the exciting new field of epigenetic biology for general readers. The surging new science of epigenetic genetics provides a veritable cornucopia of fresh insights into our bodies and minds – some unsettling, some comforting. The premise of Epigenetic’s Science is that environmental exposures can have long lasting effects on cellular function. Some of these effects are not very easy to reverse and the authors describe how”epigenetic inheritance” can lead to such disorders as cancer, Alzheimer’s disease and Parkinson’s. They also clarify the surprising effect of”epigenetic pollution,” environmental contaminants that aren’t detected by standard testing and that could cause serious health problems.
Like all living systems, cells are constantly changing and grow, divide and die. All cells need a constant supply of energy, and this procedure is initiated by a process called”mimetic induction”. Through natural selection, positive mutations accumulate over generations, and when they get together, these cells form a type of cellular memory, or methylation state. This methylation state is passed between generations and determines how cells in one family will act in response to environmental challenges and how those cells will respond when similar challenges arise in a different household member.
When methylation is induced in a cell, the result may be a whole gamut of changes on the cell surface and in the biochemical pathways within the cell. This results in alterations in gene function and a corresponding response physically. There are a number of ways that Epigenetic’s Science presents the science of Epigenetics. By way of instance, each chapter includes an informative section addressing one of the most common Epigenetic changes that exist in all people: puberty. The chapters comprise;”Growthal Sensitivity,””Mutations in Birth,”” hormonal changes,””perinatal development,””adolescent-onset diabetes,” and”nutrition.” I enjoyed each of these and found them to be very interesting and educational.
As you know, during adolescence, the body increases its production of estrogen (in anticipation of future pregnancy), and in turn, produces DHT (which stands for”dihydrotestosterone”). DHT subsequently binds to the hair follicles, which makes it difficult for nutrients to reach the roots. This causes baldness in a condition known as”male pattern baldness” Interestingly, this isn’t the only cause of hair loss, since there are other environmental and genetic factors that contribute to hair loss. Epigenetic science goes a step further and suggests that these other causes of hair loss may also be affected by methylation, so future research may shed even more light on Epigenetic’s Science.
The next topic that Epigenetic’s Science touches on is the effect that diet has on the body. Specifically, Epigenetic’s Science goes into detail about the effect that diet has on mice, worms, and other organisms. To begin with, one interesting finding was that when the worm C. elegans has been given a high fat diet, it became obese and diabetic. Interestingly, the lab animals also lost muscle mass, which is suggestive of insulin resistance. In another experiment, the lab animals were put on a special type of diet where they only received food that contained carbohydrates; they lost body fat fairly quickly.
In order to understand what’s going on here, you have to have a look at the Epigenetic’s Science methodology. Basically, they’re growing yeast in lab cultures and watching what happens. After the yeast grows to a certain point, it is going to replicate and thus create a new generation of yeast cells. In cases like this, the creation of cells has been used to study insulin resistance, something that we humans have.
Needless to say, there are additional Epigenetic’s Science techniques they use, such as gene regulation and the study of cancerous tumors. In actuality, they have recently established a successful clinical trial in which they’re attempting to treat Alzheimer’s disease in mice. As exciting as that may sound, it is not your everyday normal cancer treatment. This study shows they are able to manipulate and regulate cells and halt the growth of cancerous tumors.
Besides diabetes, Epigenetic’s Science can be used for other kinds of diseases and ailments, such as Parkinson’s, arthritis, Multiple Sclerosis, and even cancer. Needless to say, these studies are very small so we do not have much of a sense of what they will mean for human health. Still, it’s an exciting and very promising prospect. Just think, one day you could be able to grow your own cells for immune system support and energy generation; essentially creating your own drug factory!