Epigenetic’s Science is composed by award winning author, Raoul Pedretta. Great bye, genetically encoded genes… the first book in the exciting new field of epigenetic biology for general readers. The surging new science of epigenetic genetics provides a veritable cornucopia of new insights into our own bodies and minds – some unsettling, some reassuring. The premise of Epigenetic’s Science is that environmental exposures can have long lasting effects on cellular function. Some of these effects are not so easy to reverse and the authors describe how”epigenetic inheritance” can lead to such illnesses as cancer, Alzheimer’s disease and Parkinson’s. They also describe the surprising effect of”epigenetic pollution,” environmental contaminants that are not detected by standard testing and that could cause severe health problems.
Like all living systems, cells are constantly changing and grow, divide and die. All cells need a constant supply of energy, and this procedure is initiated by a process referred to as”mimetic induction”. Through natural selection, favorable mutations accumulate over generations, and if they get together, these cells form a sort of cellular memory, or methylation state. This methylation state is passed on between generations and decides how cells in 1 family will act in response to environmental challenges and how those cells will respond when similar challenges arise in another family member.
When methylation is induced in a cell, the result may be a whole gamut of changes on the cell surface and in the biochemical pathways within the cell. This causes alterations in gene function and a corresponding reaction physically. There are many ways in which Epigenetic’s Science presents the science of Epigenetics. For instance, each chapter contains an informative section covering among the most common Epigenetic changes that occur in all of us: puberty. The chapters include;”Growthal Sensitivity,””Mutations at Birth,”” hormonal changes,””perinatal development,””adolescent-onset diabetes,” and”nutrition.” I enjoyed each of these and found them to be quite interesting and educational.
As you know, during adolescence, the body increases its production of estrogen (in anticipation of future pregnancy), and in turn, produces DHT (which stands for”dihydrotestosterone”). DHT subsequently binds to the hair follicles, which makes it difficult for nutrients to reach the roots. This causes baldness in men and a condition called”male pattern baldness.” Interestingly, this is not the only cause of hair loss, as there are other genetic and environmental factors that contribute to hair loss. Epigenetic science goes a step further and suggests that these other causes of hair loss may also be affected by methylation, so future study may shed more light on Epigenetic’s Science.
The next topic that Epigenetic’s Science touches on is the effect that diet has on the body. Specifically, Epigenetic’s Science goes into detail concerning the impact that diet has on rats, rodents, and other organisms. To begin with, one interesting finding was that when the worm C. elegans was given a high fat diet, it became diabetic and obese. Interestingly, the lab animals also lost muscle mass, which is indicative of insulin resistance. In another experiment, the lab animals were put on a particular sort of diet where they only received food which contained carbohydrates; they lost body weight fairly quickly.
So as to understand what’s happening here, you must take a look at the Epigenetic’s Science methodology. Fundamentally, they are growing yeast in lab cultures and watching what happens. After the yeast grows to a certain point, it will replicate and thus create a new production of yeast cells. In cases like this, the creation of cells has been used to study insulin resistance, something that we humans have.
Of course, there are other Epigenetic’s Science techniques that they use, including gene regulation and the study of cancerous tumors. In fact, they have recently established a successful clinical trial where they’re trying to treat Alzheimer’s disease in mice. As exciting as that may sound, it’s not your everyday normal cancer therapy. This study shows that they are able to control and regulate cells and halt the growth of cancerous tumors.
Besides diabetes, Epigenetic’s Science may be used for other kinds of diseases and ailments, such as Parkinson’s, arthritis, Multiple Sclerosis, and even cancer. Needless to say, these studies are extremely small so we don’t have much of a sense of what they will mean for human health. Still, it’s an exciting and very promising prospect. Just think, one day you might have the ability to grow your own cells for immune system support and energy production; essentially creating your very own drug factory!