Epigenetic’s Science is written by award winning writer, Raoul Pedretta. Great bye, genetically encoded genes… the first book in the exciting new field of epigenetic biology for general readers. The surging new science of epigenetic genetics provides a veritable cornucopia of new insights into our own bodies and minds – some unsettling, some comforting. The premise of Epigenetic’s Science is that environmental exposures can have long lasting effects on cellular function. Some of these effects aren’t very easy to reverse and the authors describe how”epigenetic inheritance” can lead to such disorders as cancer, Alzheimer’s disease and Parkinson’s. They also describe the surprising effect of”epigenetic pollution,” environmental contaminants that aren’t detected by standard testing and that could cause severe health issues.
Like all living systems, cells are constantly changing and grow, divide and die. All cells require a constant supply of energy, and this procedure is initiated by a process referred to as”mimetic induction”. Through natural selection, favorable mutations accumulate over generations, and when they get together, these cells form a type of cellular memory, or methylation state. This methylation state is passed between generations and decides how cells in one family will behave in response to environmental challenges and how those cells will respond when similar challenges arise in another household member.
When methylation is induced in a cell, the result can be a whole gamut of changes on the cell surface and in the biochemical pathways inside the cell. This causes alterations in gene function and a corresponding reaction on the body. There are a number of ways in which Epigenetic’s Science presents the science of Epigenetics. For instance, each chapter contains an informative section covering among the most frequent Epigenetic changes which occur in all of us: puberty. The chapters comprise;”Growthal Sensitivity,””Mutations in Birth,”” hormonal changes,””perinatal development,””adolescent-onset diabetes,” and”nutrition.” I enjoyed each of them and found them to be very interesting and educational.
As you know, during adolescence, the body increases its production of estrogen (in anticipation of future pregnancy), and then, produces DHT (which stands for”dihydrotestosterone”). DHT subsequently binds to the hair follicles, making it difficult for nutrients to reach the roots. This causes baldness in men and a condition known as”male pattern baldness.” Interestingly, this isn’t the only cause of hair loss, since there are other genetic and environmental factors that contribute to hair loss. Epigenetic science goes a step further and suggests that these other causes of hair loss may also be affected by methylation, so future study might shed more light on Epigenetic’s Science.
The next topic that Epigenetic’s Science touches on is the impact that diet has on the body. Specifically, Epigenetic’s Science goes into detail about the impact that diet has on rats, rodents, and other organisms. To start with, one interesting finding was that when the worm C. elegans was given a high fat diet, it became diabetic and obese. Interestingly, the lab animals also lost muscle mass, which is indicative of insulin resistance. In another experiment, the laboratory animals were put on a particular type of diet where they only received food which contained carbohydrates; they lost body weight fairly rapidly.
So as to understand what is happening here, you must have a look at the Epigenetic’s Science methodology. Basically, they are growing yeast in laboratory cultures and watching what happens. After the yeast grows to a certain point, it is going to replicate and thus create a new generation of yeast cells. In cases like this, the creation of cells was used to study insulin resistance, something that we humans possess.
Of course, there are other Epigenetic’s Science techniques that they use, including gene regulation and the analysis of cancerous tumors. In fact, they have recently established a successful clinical trial where they’re trying to treat Alzheimer’s disease in mice. As exciting as that may sound, it is not your everyday normal cancer therapy. This study shows they are able to manipulate and regulate cells and stop the growth of cancerous tumors.
Besides diabetes, Epigenetic’s Science may be used for other kinds of diseases and conditions, such as Parkinson’s, arthritis, Multiple Sclerosis, and even cancer. Of course, these studies are extremely small so we do not have much of a sense of what they will mean for human health. Still, it is an exciting and very promising prospect. Just think, one day you could have the ability to grow your own cells for immune system support and energy production; essentially creating your own drug factory!