Epigenetic’s Science is composed by award winning author, Raoul Pedretta. Good bye, genetically encoded genes… the first book in the exciting new field of epigenetic biology for general readers. The surging new science of epigenetic genetics provides a veritable cornucopia of fresh insights into our bodies and minds – some unsettling, some comforting. The assumption of Epigenetic’s Science is the fact that environmental exposures can have long lasting effects on cellular function. Some of these effects are not so easy to reverse and the authors describe how”epigenetic inheritance” can lead to such illnesses as cancer, Alzheimer’s disease and Parkinson’s. They also describe the surprising effect of”epigenetic pollution,” environmental contaminants which are not detected by standard testing and that can cause severe health problems.
Like all living systems, cells are constantly changing and grow, divide and die. All cells need a constant supply of energy, and this process is initiated by a process referred to as”mimetic induction”. Through natural selection, favorable mutations accumulate over generations, and when they get together, these cells form a sort of cellular memory, or methylation state. This methylation state is passed on between generations and determines how cells in 1 family will act in response to environmental challenges and how those cells will respond when similar challenges arise in a different family member.
When methylation is induced in a cell, the result can be a whole gamut of changes on the cell surface and in the biochemical pathways within the cell. This causes alterations in gene function and a corresponding reaction physically. There are many ways that Epigenetic’s Science presents the science of Epigenetics. For example, each chapter contains an informative section covering among the most common Epigenetic changes which occur in all people: puberty. The chapters comprise;”Growthal Sensitivity,””Mutations at Birth,”” hormonal changes,””perinatal development,””adolescent-onset diabetes,” and”nutrition.” I enjoyed each of them and found them to be quite interesting and educational.
As you know, during adolescence, the body increases its production of estrogen (in anticipation of future pregnancy), and then, produces DHT (which stands for”dihydrotestosterone”). DHT subsequently binds to the hair follicles, which makes it difficult for nutrients to reach the roots. This causes baldness in a condition known as”male pattern baldness.” Interestingly, this isn’t the only cause of hair loss, since there are other environmental and genetic factors that contribute to hair loss. Epigenetic science goes a step further and suggests that these other causes of hair loss may also be influenced by methylation, so future study may shed more light on Epigenetic’s Science.
The next topic that Epigenetic’s Science touches on is the impact that diet has on the body. In particular, Epigenetic’s Science goes into detail concerning the impact that diet has on mice, worms, and other organisms. To begin with, one interesting finding was that when the worm C. elegans has been given a high fat diet, it became diabetic and obese. Interestingly, the laboratory animals also lost muscle mass, which is indicative of insulin resistance. In another experiment, the lab animals were put on a particular type of diet where they only received food which contained carbohydrates; they lost body weight fairly quickly.
So as to understand what’s going on here, you must take a look at the Epigenetic’s Science methodology. Fundamentally, they’re growing yeast in laboratory cultures and watching what happens. After the yeast grows to a certain point, it is going to replicate and thus create a new production of yeast cells. In this case, the creation of cells has been used to study insulin resistance, something that we humans possess.
Needless to say, there are other Epigenetic’s Science techniques they use, such as gene regulation and the analysis of cancerous tumors. In fact, they’ve recently launched a successful clinical trial where they’re trying to treat Alzheimer’s disease in mice. As exciting as that may sound, it is not your regular normal cancer therapy. This study shows that they are able to control and regulate cells and halt the growth of cancerous tumors.
Besides diabetes, Epigenetic’s Science can be used for other kinds of diseases and conditions, such as Parkinson’s, arthritis, Multiple Sclerosis, and even cancer. Of course, these studies are very small so we don’t have much of a sense of what they will mean for human health. Still, it is an exciting and very promising prospect. Just think, one day you could have the ability to grow your own cells for immune system support and energy generation; essentially creating your very own drug factory!